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Submitted
Hernadez C, Naldi A, Thomas-Chollier M, Thieffry D.  Submitted.  Computational verification of large logical models - application to the prediction of T cell response to checkpoint inhibitors.
Sánchez-Osorio I, Hernández-Martínez1 CA, Martínez-Antonio A.  Submitted.  Exploring Asymmetric Cell Division in Caulobacter Crescentus Using Logic Modeling.
Corral-Jara KF, Chauvin C, Abou-Joudé W, Grandclaudon M, Naldi A, Soumelis V, Thieffry D.  Submitted.  Interplay between Smad2 and STAT5A is a critical determinant of IL- 17A/IL-17F differential expression..
Enciso J, Mayani H, Mendoza L, Pelayo R.  Submitted.  Modeling the pro-inflammatory tumor microenvironment in acute lymphoblastic leukemia predicts a breakdown of hematopoieticmesenchymal communication networks..
Montagud A, Béal J, Tobalina L, Traynard P, Subramanian V, Szalai B, Alföldi R, Puskás L, Valencia A, Barillot E et al..  Submitted.  Patient-specific Boolean models of signaling networks guide personalized treatments.
2024
Sánchez-Villanueva J, N’Guyen L, Poplineau M, Duprez E, Remy É, Thieffry D.  2024.  Dynamical modelling of the regulatory network underlying Retinoic Acid resistance in Acute Promyelocytic Leukaemia. preprint.
2021
Nuñez-Reza KJ, Naldi A, Sánchez-Jiménez A, Leon-Apodaca AV, Santana A, Thomas-Chollier M, Thieffry D, Medina-Rivera A.  2021.  Logical modeling of in vitro differentiation of human monocytes into dendritic cells unravels novel transcriptional regulatory interactions.
Béal J, Pantolini L, Noël V, Barillot E, Calzone L.  2021.  Personalized logical models to investigate cancer response to BRAF treatments in melanomas and colorectal cancers. PLoS Comput. Biol..
2020
Selvaggio G, Canato S, Pawar A, Monteiro PT, Janody F, Chaouiya C.  2020.  Hybrid epithelial-mesenchymal phenotypes are controlled by microenvironmental factors. Cancer Research.
Kondratova M, Barillot E, Zinovyev A, Calzone L.  2020.   Modelling of Immune Checkpoint Network Explains Synergistic Effects of Combined Immune Checkpoint Inhibitor Therapy and the Impact of Cytokines in Patient Response . Cancers. 12(12)
Floc’hlay S, Molina MD, Hernandez C, Haillot E, Thomas-Chollier M, Lepage T, Thieffry D.  2020.  Deciphering and modelling the TGF-β signalling interplays specifying the dorsal-ventral axis of the sea urchin embryo. Development.
Checcoli A, Pol JG, Naldi A, Noel V, Barillot E, Kroemer G, Thieffry D, Calzone L, Stoll G.  2020.  Dynamical Boolean Modeling of Immunogenic Cell Death.
Cacace E, Collombet S, Thieffry D.  2020.  Logical modeling of cell fate specification - Application to T cell commitment. Current Topics in Developmental Biology.
2019
Sizek H, Hamel A, Deritei D, Campbell S, Regan ER.  2019.  Boolean model of growth signaling, cell cycle and apoptosis predicts the molecular mechanism of aberrant cell cycle progression driven by hyperactive PI3K. PLOS Computational Biology. 15(3)
Sanchez-Villanueva JA, Rodriguez-Jorge O, Ramirez-Pliego O, Rosas-Salgado G, Abou-Jaoudé W, Hernandez C, Naldi A, Thieffry D, Santana MA.  2019.  Contribution of ROS and metabolic status to neonatal and adult CD8+ T cell activation. PLoS One.
Rodríguez-Jorge O, Kempis-Calanis LA, Abou-Jaoudé W, Gutiérrez-Reyna DY, Hernandez C, Ramirez-Pliego O, Thomas-Chollier M, Spicuglia S, Santana MA, Thieffry D.  2019.  Cooperation between T cell receptor and Toll-like receptor 5 signaling for CD4+ T cell activation.. Science Signaling.
2018
Letort G, Montagud A, Stoll G, Heiland R, Calzone EBAZL, Macklin P.  2018.  PhysiBoSS: a multi-scale agent-based modelling framework integrating physical dimension and cell signalling. Bioinformatics. 35(7):1188–1196.
Zanudo JGT, Steinway SN, Albert R.  2018.  Discrete dynamic network modeling of oncogenic signaling: Mechanistic insights for personalized treatment of cancer. Current Opinion in Systems Biology. 9:1-10.
Sánchez L, Chaouiya C.  2018.  Logical modelling uncovers developmental constraints in primary sex determination of chicken gonads. J. R. Soc. Interface. . 15
2017
Collombet S, van Oevelen C, Sardina Ortega JL, Abou-Jaoudé W, Di Stefano B, Thomas-Chollier M, Graf T, Thieffry D.  2017.  Logical modeling of lymphoid and myeloid cell specification and transdifferentiation.. Proceedings of the National Academy of Sciences of the United States of America. 114(23):5792-5799. Abstract
Sánchez-Osorio I, Hernández-Martínez CA, Martínez-Antonio A.  2017.  Modeling Asymmetric Cell Division in Caulobacter crescentus Using a Boolean Logic Approach.. Results and problems in cell differentiation. 61:1-21. Abstract
2016
Sánchez L, Chaouiya C.  2016.  Primary sex determination of placental mammals: a modelling study uncovers dynamical developmental constraints in the formation of Sertoli and granulosa cells.. BMC systems biology. 10(1):37. Abstract
Mbodj A, Gustafson HE, Ciglar L, Junion G, GONZALEZ A, GIRARDOT C, PERRIN L, Furlong EEM, Thieffry D.  2016.  Qualitative Dynamical Modelling Can Formally Explain Mesoderm Specification and Predict Novel Developmental Phenotypes. PLoS Comput Biol. 12:1-17. Abstract
Verlingue L, Dugourd A, Stoll G, Barillot E, Calzone L, Londoño-Vallejo A.  2016.  A comprehensive approach to the molecular determinants of lifespan using a Boolean model of geroconversion. Aging Cell. :n/a–n/a.
Traynard P, Fauré A, Fages F, Thieffry D.  2016.  Logical model specification aided by model-checking techniques: application to the mammalian cell cycle regulation. Bioinformatics. 32:i772-i780. Abstract


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