%0 Journal Article %J Current opinion in genetics & development %D 2000 %T Toll signaling: the enigma variations. %A Wasserman, S A %K Animals %K Drosophila %K Drosophila Proteins %K Humans %K Insect Proteins %K Membrane Glycoproteins %K Receptors, Cell Surface %K Receptors, Immunologic %K Signal Transduction %K Toll-Like Receptor 5 %K Toll-Like Receptors %N 5 %P 497-502 %V 10 %X Experiments reported in the past year have revealed considerable diversity in Toll-mediated pathways for signal transduction in development and innate immunity. Rather than function as a well conserved signaling cassette, Toll receptors and associated factors have apparently evolved as a diverse set of configurations to defend against microbial infection in species ranging from plants to humans. %8 2000 Oct